The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration
Autores: Chang CH, Tsai WC, Lin MS, Hsu YH, Pang JH
Revista
J Appl Physiol (1985)
Año
2011
Citas
300
Type
Animal Study
Subject
Human
Condition
Wound Healing / Tissue Repair
TL;DR
BPC 157 significantly accelerated tendon explant outgrowth, cell survival, and cell migration in rat Achilles tendon transection, enhancing tendon healing.
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DOI: 10.1152/japplphysiol.00945.2010
Abstract
Pentadecapeptide BPC 157, composed of 15 amino acids, is a partial sequence of body protection compound (BPC) that is discovered in and isolated from human gastric juice.. Experimentally it has been demonstrated to accelerate the healing of many different wounds, including transected rat Achilles tendon.. This study was designed to investigate the potential mechanism of BPC 157 to enhance healing.