Sermorelin

FDA-approved GHRH analog for growth hormone deficiency diagnosis

4.5
2 리뷰

Rating Breakdown

GH Release Potency
4.0
IGF-1 Elevation
3.5
Muscle Preservation
3.5
Fat Loss Support
3.0
Sleep Quality Improvement
4.5
Safety & Side Effects
5.0
Anti-Aging Effect
4.5
Cost Effectiveness
3.0

개요

Sermorelin is the shortest functional fragment of GHRH (29 amino acids) and is one of the few peptides that has been FDA-approved for diagnostic use.

Key Information

Identity
Also Known As Geref; GRF(1-29)
Sequence Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Phe-Val-Lys-Trp-Ala
CAS Number 86168-78-7
Molecular Formula C149H246N50O42
Properties
Half-Life 10-20 minutes
Administration subcutaneous injection
Dosage Range 0.2-0.3 mg daily
Price Range $0.8–$6.0/mg
Handling & Storage
Storage Lyophilized: -20C; Reconstituted: 2-8C
Reconstitution Reconstitute with bacteriostatic water
Regulatory Status
US Status FDA-approved (diagnostic)
Legal Status FDA-approved for diagnostic use (Geref). Available via prescription.
Research Papers 1 indexed

Mechanism

Stimulates the pituitary to release natural growth hormone. Shorter half-life than CJC-1295 (~10-20 minutes).

Benefits

  • FDA-approved
  • Stimulates natural GH release
  • Preserves natural GH feedback
  • Anti-aging use

Side Effects

  • Mild injection site reaction
  • Flushing
  • Headache

Contraindications

  • Active cancer
  • Pregnancy

Evidence Summary

FDA-approved for GH deficiency diagnosis. Off-label anti-aging and recovery use.

Research

FDA-approved for diagnosing GH deficiency. Off-label use for anti-aging and recovery.

View Research

Safety

Well-tolerated. FDA-approved with established safety profile.

Legal Status

FDA-approved for diagnostic use (Geref). Available via prescription.

연구

1 research papers indexed

View Research

Write a Review

Rating Breakdown

Effectiveness
4.0
Safety
5.0
Value
3.0
Overall
4.5

Based on 2 리뷰.

리뷰

FDA-approved and well-tolerated 2026-07-30
Brian M.

Sermorelin is FDA-approved which gives peace of mind. Preserves natural GH feedback loop unlike exogenous GH. Good for anti-aging protocols under doctor supervision. Effects are gradual but real.

Effectiveness: 4/5 Safety: 5/5 Value: 3/5
Best for clinical anti-aging 2026-06-02
Mike R.

Been on sermorelin for 6 months through my longevity clinic. Sleep improved, skin elasticity better, body fat down 4%. The fact it's FDA-approved and preserves natural feedback is why I chose it.

Effectiveness: 4/5 Safety: 5/5 Value: 3/5